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Human coronavirus (hcov) is one of the most common causes of respiratory tract infection throughout the world. To investigate the epidemiological and genetic variation of hcov in guangzhou, south china, we collected totally 13048 throat and nasal swab specimens from adults and children with fever and acute upper respiratory infection symptoms in gunazhou, south china between july 2010 and june 2015, and the epidemiological features of hcov and its species were studied. Specimens were screened for hcov by real-time RT-PCR, and 7 other common respiratory viruses were tested simultaneously by PCR or real-time PCR.


HCoV was detected in 294 cases (2.25%) of the 13048 samples, with most of them inpatients (251 cases, 85.4% of hcov positive cases) and young children not in nursery (53.06%, 156 out of 294 hcov positive cases).What is anoxic encephalopathy four hcovs, as OC43, 229E, NL63 and HKU1 were detected prevalent during 2010-2015 in guangzhou, and among the hcov positive cases, 60.20% were OC43, 16.67% were 229E, 14.97% were NL63 and 7.82% were HKU1. The month distribution showed that totally hcov was prevalent in winter, but differences existed in different species. The 5 year distribution of hcov showed a peak-valley distribution trend, with the detection rate higher in 2011 and 2013 whereas lower in 2010, 2012 and 2014. The age distribution revealed that children (especially those 50 years) were both high risk groups to be infected by hcov. Of the 294 hcov positive patients, 34.69% (101 cases) were co-infected by other common respiratory viruses, and influenza virus was the most common co-infecting virus (30/101, 29.70%).What is anoxic encephalopathy fifteen hcov-OC43 positive samples of 2013-2014 were selected for S gene sequencing and phylogenetic analysis, and the results showed that the 15 strains could be divided into 2 clusters in the phylogenetic tree, 12 strains of which formed a separate cluster that was closer to genotype G found in malaysia. It was revealed for the first time that genotype B and genotype G of hcov-OC43 co-circulated and the newly defined genotype G was epidemic as a dominant genotype during 2013-2014 in guanzhou, south china.

Fusobacterium necrophorum (fn), a gram-negative anaerobe, is increasingly implicated as an etiologic agent in older adolescents and young adults with sore throat. Inadequately treated fn pharyngitis may result in suppurative complications such as peritonsillar abscess and lemierre’s syndrome.What is anoxic encephalopathy data from the literature suggest that the incidence of life-threating complications in these age groups from fn pharyngitis (lemierre’s syndrome) in the united states exceeds those associated with group A beta-hemolytic streptococcal (GAS) pharyngitis (acute rheumatic fever). Using real-time PCR, we previously reported about a 10% prevalence of fn in asymptomatic medical students and about 20% in students complaining of sore throat at a university student health clinic (p = 0.009). In this study, a comprehensive microbiome analysis of the same study samples confirms that fn pharyngitis was more common than GAS pharyngitis. Eighteen patients were found to have fn OTU values exceeding an arbitrary cutoff value of 0.1, i.E.What is anoxic encephalopathy greater than 10% of total sequences, with five subjects reaching values above 0.7. By contrast only 9 patients had GAS OTU values greater than 0.1 and none exceeded 0.6. When the data were analyzed using five separate assessments of alpha diversity, in each case for fn there were statistically significant differences between fn positive_high (OTU abundance 0.1) vs control, fn positive_high vs fn negative (OTU abundance = 0), fn positive_high vs fn positive_low (OTU abundance 0 and 0.1). When the data were analyzed using three beta diversity indexes (bray-curtis, weighted unifrac, and unweighted unifrac), there were statistically significant differences between fn positive_high (OTU abundance ≥ 0.1) vs control for all three.What is anoxic encephalopathy statistically significant differences remained if we chose somewhat different OTU abundance cutoffs of 0.05 or 0.15. We conclude that fn appears to play a dominant role in bacterial pharyngitis in the older adolescent and young adult age groups and that the development of a productive mucosal infection with fn is linked to a significant decrease in the diversity of the associated tonsillar microbiome.

The increasing number of refugees, migrants and international travelers influences the surgical spectrum of abdominal diseases. The aim of this review is to familiarize surgeons with specific diseases which are endemic in the patients’ countries of origin and are likely to be diagnosed with increasing incidence in germany.What is anoxic encephalopathy low levels of hygiene in the countries of origin or refugee camps is associated with a high incidence of numerous infections, such as helminth infections, typhoid fever or amoebiasis, which if untreated can cause surgical emergencies. Historically, some of them were common in germany but have been more or less eradicated because of the high socioeconomic standard. Echinococcosis and chagas disease are frequently treated surgically while schistosomiasis can mimic intestinal cancer. Abdominal tuberculosis presents in a variety of abdominal pathologies and frequently causes diagnostic uncertainty. Sigmoid volvulus has a very low incidence among europeans, but is one of the most common abdominal surgical conditions of adults in endemic countries.What is anoxic encephalopathy the number of patients who eventually undergo surgery for these conditions might be relatively low; however, surgeons must be aware of them and consider them as differential diagnoses in refugees and migrants with acute or chronic abdominal symptoms.

The present case report describes a rare case of T cell acute lymphoblastic lymphoma (T-LBL) in the lymph node with myeloid sarcoma in the pericardium. A 33-year-old chinese male was admitted to hospital on 4 july 2015 exhibiting a fever and having experienced wheezing and fatigue for the previous 7 days. Routine pathological, computed tomographic, cytological and immunophenotypic observations revealed a diagnosis of T-LBL in the lymph node on 7 august 2015, without evidence of bone marrow (BM) involvement.What is anoxic encephalopathy the patient received induction chemotherapy for T-LBL and achieved partial remission. The patient was identified to have multiple serous effusion and analysis of pericardial effusion cells revealed the diagnosis of T-LBL with extramedullary myeloid sarcoma (without BM involvement) on 25 november 2015. On 30 december 2015, the patient was identified to exhibit proliferation of primary myeloid cells in the peripheral blood and BM, and an abnormal karyotype in BM cells, indicating that the complicated myeloid sarcoma involved the BM. No matched donor was available so the patient received chemotherapy to manage the disease. The patient was discharged on 31 january 2016 and ceased treatment. The patient succumbed on 19 february 2016 at home.What is anoxic encephalopathy to the best of our knowledge, T-LBL complicated with myeloid sarcoma had not been previously reported in chinese adult male patients. In addition, the involvement of the BM and aberrant karyotype of the complicated myeloid sarcoma in the patient were rare.

Arthropod-borne viruses (arboviruses) are transmitted to humans primarily through the bites of infected mosquitoes and ticks. West nile virus (WNV) is the leading cause of domestically acquired arboviral disease in the continental united states (1,2). Other arboviruses, including la crosse, powassan, jamestown canyon, st. Louis encephalitis, and eastern equine encephalitis viruses, cause sporadic cases of disease and occasional outbreaks. This report summarizes surveillance data reported to CDC for 2016 for nationally notifiable arboviruses.What is anoxic encephalopathy it excludes dengue, chikungunya, and zika viruses, as these are primarily nondomestic viruses typically acquired through travel. Forty-seven states and the district of columbia (DC) reported 2,240 cases of domestic arboviral disease, including 2,150 (96%) WNV disease cases. Of the WNV disease cases, 1,310 (61%) were classified as neuroinvasive disease (e.G., meningitis, encephalitis, acute flaccid paralysis), for a national incidence of 0.41 cases per 100,000 population. After WNV, the most frequently reported arboviruses were la crosse (35 cases), powassan (22), and jamestown canyon (15) viruses. Because arboviral diseases continue to cause serious illness, maintaining surveillance is important to direct prevention activities.What is anoxic encephalopathy

Spontaneous or nosocomial escherichia coli meningitis remains rare in healthy adults but is still carrying a high mortality rate despite adapted antimicrobial treatment for susceptible strains. A 39-year-old woman was admitted to the hospital with severe subarachnoid haemorrhage complicated by acute hydrocephalus. On hospital day 10, she developed streptococcus anginosus septicaemia and urinary tract infection due to a multisensitive strain of E. Coli. This infection was successfully controlled by antimicrobial therapy. As a late complication in the neurosurgical ward (day 39), she developed fever, alteration of consciousness, and shock, leading to the diagnosis of bacterial meningitis. The culture of blood, cerebrospinal fluid, and urine grew positive for a multisensitive E.What is anoxic encephalopathy coli. The strain was identified as O117:K52:H, a serotype that was until now never associated with acute meningitis or brain abscesses. The source appeared to be the urinary tract with the demonstration of acute pyelonephritis. The patient died on day 94 from delayed complications of multiple brain abscesses.

Objective the primary endpoint of this study was to determine the incidence of febrile neutropenia among patients receiving either moxifloxacin or levofloxacin for antibacterial prophylaxis. Secondary endpoints were number of documented infections and in-hospital mortality in patients who develop febrile neutropenia. Methods A single-center retrospective cohort analysis at a large tertiary care academic medical center was conducted.What is anoxic encephalopathy this study included adult acute leukemia patients (age ≥18 years old) who received inpatient antibacterial prophylaxis (moxifloxacin or levofloxacin) from 1 july 2012 to 1 october 2014. Patients were excluded from the study if they were treated with antimicrobial therapy in the preceding five days or admitted to the hospital with neutropenic fever. Fisher’s exact test was used for categorical data and mann-whitney test for continuous data. Logistic regression analysis was used to determine risk factors for febrile neutropenia. Results eighty-five patients were included in the final analysis with 40 patients who received moxifloxacin and 45 patients who received levofloxacin. Baseline characteristics were similar between the two groups.What is anoxic encephalopathy twenty-two patients experienced febrile neutropenia requiring intravenous antibiotics in the moxifloxacin group and 30 patients in the levofloxacin group (P = 0.190). Age and duration of neutropenia appeared to predict for febrile neutropenia; however, after multivariate analysis, longer duration of neutropenia was shown to be the best predictor for febrile neutropenia with an odds ratio of 4.69 (95% CI, 1.697-12.968). Both groups had similar rates of documented infections and in-hospital morality. Conclusion moxifloxacin and levofloxacin showed similar rates of febrile neutropenia when used for neutropenic antibacterial prophylaxis in acute leukemia patients.