Minerva neurosciences reports third quarter 2018 financial results and business updates hypoxic brain damage treatment

Data readouts from five ongoing late-stage trials expected in 2019 WALTHAM, Mass., Nov. 05, 2018 (GLOBE NEWSWIRE) — Minerva Neurosciences, Inc. (NASDAQ: NERV), a clinical-stage biopharmaceutical company focused on the development of therapies to treat central nervous system (CNS) disorders, today reported key business updates and financial results for the quarter ended September 30, 2018. […]

WALTHAM, Mass., Nov. 05, 2018 (GLOBE NEWSWIRE) — Minerva Neurosciences, Inc. (NASDAQ: NERV), a clinical-stage biopharmaceutical company focused on the development of therapies to treat central nervous system (CNS) disorders, today reported key business updates and financial results for the quarter ended September 30, 2018.


“Over the last quarter, we have continued to enroll patients into five clinical trials with roluperidone (MIN-101), seltorexant (MIN-202) and MIN-117,” said Dr. anxiety disorder icd 10 Remy Luthringer, Executive Chairman and Chief Executive Officer of Minerva. “Momentum continues to build in the enrollment of patients in our Phase 3 trial with roluperidone. We are nearing our target number of clinical sites, including certain sites initiated following the decision by two eastern European countries not to participate in this trial. We expect the completion of enrollment during the first half of 2019 and top-line results in mid-2019.

“All other trials are proceeding on schedule with existing data readout timelines, as we have previously guided,” said Dr. Luthringer. “We believe that each of our clinical-stage product candidates has the potential to have a meaningful impact on the CNS therapeutic landscape and improve the quality of life of patients and their families.”

• R&D Expenses: Research and development (R&D) expenses for the three and nine months ended September 30, 2018 were $8.4 million and $25.9 million, respectively, compared to $9.0 million and $23.7 million for the same periods in 2017. This variance in R&D expenses was due to lower development expenses for the seltorexant program due to the Amendment to our Co-Development and License Agreement with Janssen, which was partially offset by higher development expenses for the Phase 3 clinical trial of roluperidone and the Phase 2b clinical trial of MIN-117.

• G&A Expenses: General and administrative (G&A) expenses for the three and nine months ended September 30, 2018 were $4.1 million and $12.2 million, respectively, compared to $2.5 million and $7.9 million for the same periods in 2017. anoxic encephalopathy icd 10 This increase in G&A expenses was primarily due to an increase in non-cash stock-based compensation expenses and salary costs from increased staffing to support pre-commercial activities.

• Net Loss: The Company reported a net loss for the three and nine months ended September 30, 2018 of $12.0 million and $37.0 million respectively, or $0.31 and $0.95 per share, respectively, compared to $11.3 million and $31.7 million, respectively, or $0.28 and $0.84 per share, respectively, for the same period in 2017.

Minerva Neurosciences will host a conference call and live audio webcast today at 8:30 a.m. Eastern Time to discuss the quarter and recent business activities. anxiété antonyme To participate, please dial (877) 312-5845 (domestic) or (765) 507-2618 (international) and refer to conference ID number 7429089.

The live webcast can be accessed under “Events and Presentations” in the Investors and Media section of Minerva’s website at ir.minervaneurosciences.com. The archived webcast will be available on the website beginning approximately two hours after the event for 90 days.

Minerva Neurosciences, Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of a portfolio of product candidates to treat CNS diseases. Minerva’s proprietary compounds include: roluperidone (MIN-101), in clinical development for schizophrenia; MIN-117, in clinical development for major depressive disorder (MDD); seltorexant (MIN-202 or JNJ-42847922), in clinical development for insomnia and MDD; and MIN-301, in pre-clinical development for Parkinson’s disease. nanoxia deep silence 120mm ultra quiet pc fan Minerva’s common stock is listed on the NASDAQ Global Market under the symbol “NERV.” For more information, please visit www.minervaneurosciences.com.

This press release contains forward-looking statements which are subject to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts, reflect management’s expectations as of the date of this press release, and involve certain risks and uncertainties. Forward-looking statements include statements herein with respect to the timing and scope of current clinical trials and results of clinical trials with roluperidone, seltorexant, MIN-117 and MIN-301; the timing and scope of future clinical trials and results of clinical trials with these compounds; the clinical and therapeutic potential of these compounds; our ability to successfully develop and commercialize our therapeutic products; the sufficiency of our current cash position to fund our operations; and management’s ability to successfully achieve its goals. These forward-looking statements are based on our current expectations and may differ materially from actual results due to a variety of factors including, without limitation, whether roluperidone, seltorexant, MIN-117 and MIN-301 will advance further in the clinical trials process and whether and when, if at all, they will receive final approval from the U.S. Food and Drug Administration or equivalent foreign regulatory agencies and for which indications; whether any of our therapeutic products will be successfully marketed if approved; whether any of our therapeutic product discovery and development efforts will be successful; management’s ability to successfully achieve its goals; our ability to raise additional capital to fund our operations on terms acceptable to us; and general economic conditions. These and other potential risks and uncertainties that could cause actual results to differ from the results predicted are more fully detailed under the caption “Risk Factors” in our filings with the Securities and Exchange Commission, including our Quarterly Report on Form 10-Q for the quarter ended September 30, 2018, filed with the Securities and Exchange Commission on November 5, 2018. Copies of reports filed with the SEC are posted on our website at www.minervaneurosciences.com. definicion de anorexia wikipedia The forward-looking statements in this press release are based on information available to us as of the date hereof, and we disclaim any obligation to update any forward-looking statements, except as required by law.